haemoglobin$33394$ - translation to ολλανδικά
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haemoglobin$33394$ - translation to ολλανδικά

VARIANT OF HEMOGLOBIN A
Hemoglobin a2; Haemoglobin a2; Haemoglobin A2; Hb A2

haemoglobin      
n. hemoglobine, bloedkleurstof, de ijzerhoudende kleurstof der rode bloedlichaampjes
sickle cell anemia         
  • Normal blood cells next to a sickle blood cell, coloured scanning electron microscope image
  • Sickle cell disease is inherited in an [[autosomal recessive]] pattern.
  • located]] on the short (p) arm of [[chromosome 11]] at position 15.5.
  • Historical distribution of [[malaria]] (no longer endemic in Europe), shown in green
  • Modern distribution of malaria
  • Percentage of newborns screened for sickle cell disease within Metropolitan France from 2006 to 2018
  • Sickle cell anaemia
  • Base-pair substitution that causes sickle cell anemia
  • Possible advantage of being heterozygous for sickle cell anemia disease (A) vs. normal blood cell response (B) when infected with malaria
  • Percentage of newborns screened regionally and overall for sickle cell disease in Metropolitan France in 2018
  • Distribution of the sickle cell trait, shown in pink and purple
  • Sickle cells in human blood - both normal red blood cells and sickle-shaped cells are present.
  • [[Scanning electron micrograph]] showing a mixture of red blood cells, some with round normal morphology, some with mild sickling showing elongation and bending
GROUP OF GENETIC BLOOD DISORDERS
Sickle cell anaemia; Sickle-cell anaemia; Sickle Cell Anemia; Sickle Cell Disease; Sickle cell; Sickle cell crisis; Sickle cell anemia; Sickle-cell anemia; Sickle-cell disorders; Anemia, sickle cell; Hemoglobin, sickle; Sickle-cell Anemia; Sickle cells; Sickle Cell disease; Sickle-cell; Depranocytosis; Sickle cell test; Haemoglobin S; Hemoglobin S; Hb S; Drepanocytosis; Sick-as-hell anemia; Sickledex; Sickle-Cell Anemia; Drepanocyte; Sickling; Sickling crisis; Sickle cell disorder; World Sickle Cell Day; Sickle cell disorders; Keone's Law; Keone's law; Saving the Cure Act; Keone Penn; Drépanocytose; Hemoglobin s; Sickle Cell Anaemia; Sickle-cell haemoglobin; Sickle-cell disease; Gene therapy for sickle cell disease; Sickle cell hemoglobin; Sickle solubility test; Sickle hemoglobin; Management of sickle cell disease
sikkelanemie, vorm van erfelijke hemoglobinopathie, gekenmerkt door aanwezigheid van sikkelvormige erytrocyten, miltvergroting, icterus en gebrek aan vorming van hemoglobine

Ορισμός

Hemoglobin
·noun The normal coloring matter of the red blood corpuscles of vertebrate animals. It is composed of hematin and globulin, and is also called haematoglobulin. In arterial blood, it is always combined with oxygen, and is then called oxyhemoglobin. It crystallizes under different forms from different animals, and when crystallized, is called haematocrystallin. ·see Blood crystal, under Blood.

Βικιπαίδεια

Hemoglobin A2

Hemoglobin A2 (HbA2) is a normal variant of hemoglobin A that consists of two alpha and two delta chains (α2δ2) and is found at low levels in normal human blood. Hemoglobin A2 may be increased in beta thalassemia or in people who are heterozygous for the beta thalassemia gene.

HbA2 exists in small amounts in all adult humans (1.5–3.1% of all hemoglobin molecules) and is approximately normal in people with sickle-cell disease. Its biological importance is not yet known.